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Found 1 hit Enz. Inhib. hit(s) with Target = 'Replicative DNA helicase' and Ligand = 'BDBM50400424'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replicative DNA helicase


(Bacillus anthracis)		BDBM50400424
PNG
(CHEMBL2178448)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccc(Cl)c(Cl)c2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C27H22Cl2O5/c1-15-20-8-11-24(16(2)26(20)34-27(32)21(15)9-12-25(30)31)33-14-17-3-5-18(6-4-17)19-7-10-22(28)23(29)13-19/h3-8,10-11,13H,9,12,14H2,1-2H3,(H,30,31)
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay

J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair