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Found 1 hit Enz. Inhib. hit(s) with Target = 'Replicative DNA helicase' and Ligand = 'BDBM50400435'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replicative DNA helicase


(Bacillus anthracis)		BDBM50400435
PNG
(CHEMBL2177806)
Show SMILES Cc1c(OCc2c3ccccc3cc3ccccc23)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C29H24O5/c1-17-21-11-13-26(18(2)28(21)34-29(32)22(17)12-14-27(30)31)33-16-25-23-9-5-3-7-19(23)15-20-8-4-6-10-24(20)25/h3-11,13,15H,12,14,16H2,1-2H3,(H,30,31)
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.20E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay

J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair