Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta' and Ligand = 'BDBM50019795'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019795 (CHEMBL3286887) Show SMILES OC(=O)CC(COc1ccc(cc1)-c1nc2ccccc2n1Cc1ccccc1)n1c(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C37H30N4O3/c42-35(43)23-29(41-34-18-10-8-16-32(34)39-37(41)27-13-5-2-6-14-27)25-44-30-21-19-28(20-22-30)36-38-31-15-7-9-17-33(31)40(36)24-26-11-3-1-4-12-26/h1-22,29H,23-25H2,(H,42,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair