Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta' and Ligand = 'BDBM50019811'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019811 (CHEMBL3286896) Show SMILES Cc1ccccc1Cn1c(nc2ccccc12)-c1ccc(OCC(C2CCNCC2)n2c(nc3ccccc23)-c2ccccc2)cc1 Show InChI InChI=1S/C41H39N5O/c1-29-11-5-6-14-33(29)27-45-37-17-9-7-15-35(37)43-40(45)32-19-21-34(22-20-32)47-28-39(30-23-25-42-26-24-30)46-38-18-10-8-16-36(38)44-41(46)31-12-3-2-4-13-31/h2-22,30,39,42H,23-28H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	474	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair