Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta' and Ligand = 'BDBM50019816'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019816 (CHEMBL3286900) Show SMILES Fc1cccc(Cl)c1Cn1c(nc2ccccc12)N1CCC(CC1)C(=O)OCC(C1CCNCC1)n1c(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C40H40ClFN6O2/c41-31-11-8-12-32(42)30(31)25-47-35-15-6-4-13-33(35)45-40(47)46-23-19-29(20-24-46)39(49)50-26-37(27-17-21-43-22-18-27)48-36-16-7-5-14-34(36)44-38(48)28-9-2-1-3-10-28/h1-16,27,29,37,43H,17-26H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair