Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta' and Ligand = 'BDBM50019825'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019825 (CHEMBL3286905) Show SMILES O=C(OCC(C1CCNC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C39H40N6O2/c46-38(30-20-23-43(24-21-30)39-42-32-15-7-9-17-34(32)44(39)26-28-11-3-1-4-12-28)47-27-36(31-19-22-40-25-31)45-35-18-10-8-16-33(35)41-37(45)29-13-5-2-6-14-29/h1-18,30-31,36,40H,19-27H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019825 (CHEMBL3286905) Show SMILES O=C(OCC(C1CCNC1)n1c(nc2ccccc12)-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C39H40N6O2/c46-38(30-20-23-43(24-21-30)39-42-32-15-7-9-17-34(32)44(39)26-28-11-3-1-4-12-28)47-27-36(31-19-22-40-25-31)45-35-18-10-8-16-33(35)41-37(45)29-13-5-2-6-14-29/h1-18,30-31,36,40H,19-27H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair