Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta' and Ligand = 'BDBM50019844'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019844 (CHEMBL3286910) Show SMILES CC(C)c1nc2ccccc2n1[C@H](COC(=O)C1CCN(CC1)c1nc2ccccc2n1Cc1ccsc1)C1CCNCC1 |r| Show InChI InChI=1S/C35H42N6O2S/c1-24(2)33-37-29-8-4-6-10-31(29)41(33)32(26-11-16-36-17-12-26)22-43-34(42)27-13-18-39(19-14-27)35-38-28-7-3-5-9-30(28)40(35)21-25-15-20-44-23-25/h3-10,15,20,23-24,26-27,32,36H,11-14,16-19,21-22H2,1-2H3/t32-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair