Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta' and Ligand = 'BDBM50019857'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019857 (CHEMBL3286921) Show SMILES C=CC(=O)N1CCC(CC1)[C@@H](COc1ccc(cc1)-c1nc2ccccc2n1Cc1ccccc1)n1c(nc2ccccc12)-c1ccccc1 |r| Show InChI InChI=1S/C43H39N5O2/c1-2-41(49)46-27-25-32(26-28-46)40(48-39-20-12-10-18-37(39)45-43(48)33-15-7-4-8-16-33)30-50-35-23-21-34(22-24-35)42-44-36-17-9-11-19-38(36)47(42)29-31-13-5-3-6-14-31/h2-24,32,40H,1,25-30H2/t40-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair