BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor RXR-alpha' and Ligand = 'BDBM50052033'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50052033 ((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-9-cis-RA binding to Retinoid X receptor RXR alpha				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50052033 ((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	134	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing Retinoid X receptor RXR alpha				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair