BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor RXR-alpha' and Ligand = 'BDBM50299278'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50299278 (3-Fluoro-4-(1-(1,2,3,4-tetrahydro-1,1,4,4,6-pentam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	161	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Displacement of [3H]-9-cis-retinoic acid form human RXRalpha expressed in human Caco2 cells after 16 hrs				J Med Chem 52: 5950-66 (2009) Article DOI: 10.1021/jm900496b BindingDB Entry DOI: 10.7270/Q2Q81D41
Arizona State University Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50299278 (3-Fluoro-4-(1-(1,2,3,4-tetrahydro-1,1,4,4,6-pentam...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
Arizona State University Curated by ChEMBL					Assay Description Agonist activity at human recombinant Gal4-tagged RXRalpha expressed in human Caco2 cells assessed as receptor homodimerization after 24 hrs by mamma...				J Med Chem 52: 5950-66 (2009) Article DOI: 10.1021/jm900496b BindingDB Entry DOI: 10.7270/Q2Q81D41
Arizona State University Curated by ChEMBL					More data for this Ligand-Target Pair