Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM24998'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM24998 (4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrrol-2-yl)-1...) Show SMILES CCn1c(nc2c(ncc(OCCCN)c12)-c1ccc[nH]1)-c1nonc1N Show InChI InChI=1S/C17H20N8O2/c1-2-25-15-11(26-8-4-6-18)9-21-12(10-5-3-7-20-10)13(15)22-17(25)14-16(19)24-27-23-14/h3,5,7,9,20H,2,4,6,8,18H2,1H3,(H2,19,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
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