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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM50026798'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 1


(Homo sapiens (Human))		BDBM50026798
PNG
(CHEMBL1956072 | SB-742548)
Show SMILES Cl.CCn1c(nc2cncc(-c3ccc(CN)cc3)c12)-c1nonc1N
Show InChI InChI=1S/C17H17N7O.ClH/c1-2-24-15-12(11-5-3-10(7-18)4-6-11)8-20-9-13(15)21-17(24)14-16(19)23-25-22-14;/h3-6,8-9H,2,7,18H2,1H3,(H2,19,23);1H
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Similars
Article
PubMed
n/an/a<10n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant N-terminal his-tagged ROCK1 (3-543) expressed in baculovirus infected Sf9 cells using Biotin-Ahx-AKRRLSSLRA-CONH2 sub...

J Pharmacol Exp Ther 320: 89-98 (2006)


Article DOI: 10.1124/jpet.106.110635
BindingDB Entry DOI: 10.7270/Q2DV1KBV
More data for this
Ligand-Target Pair