Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM50299365'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50299365 (CHEMBL567603 | N2-(2,3-dihydro-1H-inden-1-yl)-6-(p...) Show SMILES C1Cc2ccccc2C1Nc1nc(Nc2ccncc2)nc(n1)N1CCNCC1 Show InChI InChI=1S/C21H24N8/c1-2-4-17-15(3-1)5-6-18(17)25-20-26-19(24-16-7-9-22-10-8-16)27-21(28-20)29-13-11-23-12-14-29/h1-4,7-10,18,23H,5-6,11-14H2,(H2,22,24,25,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of ROCK1 by IMAP assay				Bioorg Med Chem Lett 19: 6027-31 (2009) Article DOI: 10.1016/j.bmcl.2009.09.046 BindingDB Entry DOI: 10.7270/Q2668D7P
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