Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM50309123'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50309123 (4-(6-(piperazin-1-yl)-5-(pyrrolidin-1-yl)pyrazin-2...) Show SMILES C1CCN(C1)c1ncc(nc1N1CCNCC1)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C19H23N7/c1-2-10-25(9-1)18-19(26-11-7-20-8-12-26)24-16(13-23-18)14-3-5-21-17-15(14)4-6-22-17/h3-6,13,20H,1-2,7-12H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human recombinant ROCK1				Bioorg Med Chem Lett 20: 1137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.012 BindingDB Entry DOI: 10.7270/Q2QR4X7J
					More data for this Ligand-Target Pair