Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM50358704'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50358704 (CHEMBL1922040) Show SMILES COc1cccc(CN(CC[N+]2(C)CCCC2)C(=O)c2cc3ccc(nc3n2C)-c2cn[nH]c2)c1 Show InChI InChI=1S/C27H32N6O2/c1-31-25(16-21-9-10-24(30-26(21)31)22-17-28-29-18-22)27(34)32(11-14-33(2)12-4-5-13-33)19-20-7-6-8-23(15-20)35-3/h6-10,15-18H,4-5,11-14,19H2,1-3H3/p+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK1				Bioorg Med Chem Lett 21: 7113-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.084 BindingDB Entry DOI: 10.7270/Q2F1905N
					More data for this Ligand-Target Pair