Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM119894'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119894 (US8697911, 6) Show SMILES CN1CCc2nc(NC(=O)c3cccc(CNC(=O)c4cccc(c4)-c4cn[nH]c4)c3)sc2C1 Show InChI InChI=1S/C25H24N6O2S/c1-31-9-8-21-22(15-31)34-25(29-21)30-24(33)18-6-2-4-16(10-18)12-26-23(32)19-7-3-5-17(11-19)20-13-27-28-14-20/h2-7,10-11,13-14H,8-9,12,15H2,1H3,(H,26,32)(H,27,28)(H,29,30,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119894 (US8697911, 6) Show SMILES CN1CCc2nc(NC(=O)c3cccc(CNC(=O)c4cccc(c4)-c4cn[nH]c4)c3)sc2C1 Show InChI InChI=1S/C25H24N6O2S/c1-31-9-8-21-22(15-31)34-25(29-21)30-24(33)18-6-2-4-16(10-18)12-26-23(32)19-7-3-5-17(11-19)20-13-27-28-14-20/h2-7,10-11,13-14H,8-9,12,15H2,1H3,(H,26,32)(H,27,28)(H,29,30,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	28
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase is measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-luc...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair