Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM119914'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119914 (US8697911, 38) Show SMILES Cc1nnnn1-c1ccc(cc1)C(=O)NCc1cccc(c1)C(=O)Nc1nc2CC[C@H](N)Cc2s1 |r| Show InChI InChI=1S/C24H24N8O2S/c1-14-29-30-31-32(14)19-8-5-16(6-9-19)22(33)26-13-15-3-2-4-17(11-15)23(34)28-24-27-20-10-7-18(25)12-21(20)35-24/h2-6,8-9,11,18H,7,10,12-13,25H2,1H3,(H,26,33)(H,27,28,34)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119914 (US8697911, 38) Show SMILES Cc1nnnn1-c1ccc(cc1)C(=O)NCc1cccc(c1)C(=O)Nc1nc2CC[C@H](N)Cc2s1 |r| Show InChI InChI=1S/C24H24N8O2S/c1-14-29-30-31-32(14)19-8-5-16(6-9-19)22(33)26-13-15-3-2-4-17(11-15)23(34)28-24-27-20-10-7-18(25)12-21(20)35-24/h2-6,8-9,11,18H,7,10,12-13,25H2,1H3,(H,26,33)(H,27,28,34)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	28
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase is measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-luc...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair