Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM119957'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119957 (US8697911, 119) Show SMILES CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cc(n[nH]4)-c4ccncc4)c3)cc2C1 Show InChI InChI=1S/C27H26N6O2/c1-33-12-9-19-5-6-23(14-22(19)17-33)30-26(34)21-4-2-3-18(13-21)16-29-27(35)25-15-24(31-32-25)20-7-10-28-11-8-20/h2-8,10-11,13-15H,9,12,16-17H2,1H3,(H,29,35)(H,30,34)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119957 (US8697911, 119) Show SMILES CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cc(n[nH]4)-c4ccncc4)c3)cc2C1 Show InChI InChI=1S/C27H26N6O2/c1-33-12-9-19-5-6-23(14-22(19)17-33)30-26(34)21-4-2-3-18(13-21)16-29-27(35)25-15-24(31-32-25)20-7-10-28-11-8-20/h2-8,10-11,13-15H,9,12,16-17H2,1H3,(H,29,35)(H,30,34)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	28
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase is measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-luc...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair