Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM119969'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119969 (US8697911, 134) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(CNC(=O)c4ccc(cc4)-n4ccnc4)c3)sc2C1 |r| Show InChI InChI=1S/C27H28N6O2S/c1-32(2)22-10-11-23-24(15-22)36-27(30-23)31-26(35)20-5-3-4-18(14-20)16-29-25(34)19-6-8-21(9-7-19)33-13-12-28-17-33/h3-9,12-14,17,22H,10-11,15-16H2,1-2H3,(H,29,34)(H,30,31,35)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
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