Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM119985'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM119985 (US8697911, 168) Show SMILES Cc1nc(sc1C(=O)NCc1cccc(c1)C(=O)Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)-c1ccncc1 |r| Show InChI InChI=1S/C29H30N6O3S2/c1-18-25(40-28(32-18)20-7-9-30-10-8-20)27(37)31-17-19-3-2-4-21(15-19)26(36)34-29-33-23-6-5-22(16-24(23)39-29)35-11-13-38-14-12-35/h2-4,7-10,15,22H,5-6,11-14,16-17H2,1H3,(H,31,37)(H,33,34,36)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.370	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US8697911 (2014) BindingDB Entry DOI: 10.7270/Q25X27KR
					More data for this Ligand-Target Pair