Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM141035'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM141035 (US10570123, Example 261 | US8916576, 261) Show SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3n(ncc3c2)C(=O)OC(C)(C)C)c2cc(OCCOC)c(OC)cc2n1 Show InChI InChI=1S/C34H38N6O6/c1-7-9-30(41)36-23-11-8-10-21(16-23)31-38-26-19-28(44-6)29(45-15-14-43-5)18-25(26)32(39-31)37-24-12-13-27-22(17-24)20-35-40(27)33(42)46-34(2,3)4/h8,10-13,16-20H,7,9,14-15H2,1-6H3,(H,36,41)(H,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
SURFACE LOGIX, LLC US Patent					Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).				US Patent US10570123 (2020) BindingDB Entry DOI: 10.7270/Q2542R1V
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM141035 (US10570123, Example 261 | US8916576, 261) Show SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3n(ncc3c2)C(=O)OC(C)(C)C)c2cc(OCCOC)c(OC)cc2n1 Show InChI InChI=1S/C34H38N6O6/c1-7-9-30(41)36-23-11-8-10-21(16-23)31-38-26-19-28(44-6)29(45-15-14-43-5)18-25(26)32(39-31)37-24-12-13-27-22(17-24)20-35-40(27)33(42)46-34(2,3)4/h8,10-13,16-20H,7,9,14-15H2,1-6H3,(H,36,41)(H,37,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
Surface Logix, Inc. US Patent					Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).				US Patent US8916576 (2014) BindingDB Entry DOI: 10.7270/Q2P55M6K
					More data for this Ligand-Target Pair