Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM169496'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169496 (US9079880, 29) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3cccc(c3)C#N)sc2C1 |r| Show InChI InChI=1S/C29H32N6O2S/c1-2-13-31-22-11-12-24-26(17-22)38-28(33-24)34-27(36)21-8-4-7-20(16-21)25-10-5-14-35(25)29(37)32-23-9-3-6-19(15-23)18-30/h3-4,6-9,15-16,22,25,31H,2,5,10-14,17H2,1H3,(H,32,37)(H,33,34,36)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169496 (US9079880, 29) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3cccc(c3)C#N)sc2C1 |r| Show InChI InChI=1S/C29H32N6O2S/c1-2-13-31-22-11-12-24-26(17-22)38-28(33-24)34-27(36)21-8-4-7-20(16-21)25-10-5-14-35(25)29(37)32-23-9-3-6-19(15-23)18-30/h3-4,6-9,15-16,22,25,31H,2,5,10-14,17H2,1H3,(H,32,37)(H,33,34,36)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair