Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50005623'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50005623 (CHEMBL2024652) Show SMILES NCCCC[C@@H](NC(=O)CCNC(=O)CNCC(=O)NCCNS(=O)(=O)c1cccc2cnccc12)C(=O)NCCCCCC(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=C)C(N)=O |r| Show InChI InChI=1S/C43H72N16O9S/c1-29(45)51-20-8-12-32(40(46)64)59-42(66)34(13-9-21-55-43(47)48)58-36(60)15-3-2-6-19-54-41(65)33(11-4-5-18-44)57-37(61)17-23-52-38(62)27-50-28-39(63)53-24-25-56-69(67,68)35-14-7-10-30-26-49-22-16-31(30)35/h7,10,14,16,22,26,32-34,50-51,56H,1-6,8-9,11-13,15,17-21,23-25,27-28,44-45H2,(H2,46,64)(H,52,62)(H,53,63)(H,54,65)(H,57,61)(H,58,60)(H,59,66)(H4,47,48,55)/t32-,33-,34-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Displacement of fluorescent-ARC-1042 from His6-tagged recombinant human ROCK2 by fluorescence anisotropy assay				Bioorg Med Chem Lett 22: 3425-30 (2012) Article DOI: 10.1016/j.bmcl.2012.03.101 BindingDB Entry DOI: 10.7270/Q2GT5P5N
					More data for this Ligand-Target Pair