Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50087130'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50087130 (CHEMBL3426625) Show SMILES COC(=O)Cc1ccc(NC(=O)c2cccc(c2)-c2cc(ccc2CN)C(=O)Nc2ccncc2F)cc1 Show InChI InChI=1S/C29H25FN4O4/c1-38-27(35)13-18-5-9-23(10-6-18)33-28(36)20-4-2-3-19(14-20)24-15-21(7-8-22(24)16-31)29(37)34-26-11-12-32-17-25(26)30/h2-12,14-15,17H,13,16,31H2,1H3,(H,33,36)(H,32,34,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Agoralaan Abis Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...				J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50087130 (CHEMBL3426625) Show SMILES COC(=O)Cc1ccc(NC(=O)c2cccc(c2)-c2cc(ccc2CN)C(=O)Nc2ccncc2F)cc1 Show InChI InChI=1S/C29H25FN4O4/c1-38-27(35)13-18-5-9-23(10-6-18)33-28(36)20-4-2-3-19(14-20)24-15-21(7-8-22(24)16-31)29(37)34-26-11-12-32-17-25(26)30/h2-12,14-15,17H,13,16,31H2,1H3,(H,33,36)(H,32,34,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Agoralaan Abis Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...				J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R
					More data for this Ligand-Target Pair