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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50087136'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))
BDBM50087136
PNG
(CHEMBL3426732)
Show SMILES NCc1ccc(cc1-c1cccc(NC(=O)c2ccc(cc2)C(O)=O)c1)C(=O)Nc1ccncc1F
Show InChI InChI=1S/C27H21FN4O4/c28-23-15-30-11-10-24(23)32-26(34)19-8-9-20(14-29)22(13-19)18-2-1-3-21(12-18)31-25(33)16-4-6-17(7-5-16)27(35)36/h1-13,15H,14,29H2,(H,31,33)(H,35,36)(H,30,32,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Agoralaan Abis

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...


J Med Chem 58: 4309-24 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00308
BindingDB Entry DOI: 10.7270/Q2H41T4R
More data for this
Ligand-Target Pair