Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50087437'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50087437 (CHEMBL3426634) Show SMILES CCCOC(=O)c1ccc(F)c(NC(=O)c2cccc(c2)-c2cc(ccc2CN)C(=O)Nc2ccncc2F)c1 Show InChI InChI=1S/C30H26F2N4O4/c1-2-12-40-30(39)21-8-9-24(31)27(15-21)36-28(37)19-5-3-4-18(13-19)23-14-20(6-7-22(23)16-33)29(38)35-26-10-11-34-17-25(26)32/h3-11,13-15,17H,2,12,16,33H2,1H3,(H,36,37)(H,34,35,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Agoralaan Abis Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...				J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R
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