Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50087442'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50087442 (CHEMBL3426628) Show SMILES NCc1ccc(cc1-c1cccc(c1)C(=O)Nc1ccc(cc1)C(O)=O)C(=O)Nc1ccncc1F Show InChI InChI=1S/C27H21FN4O4/c28-23-15-30-11-10-24(23)32-26(34)19-4-5-20(14-29)22(13-19)17-2-1-3-18(12-17)25(33)31-21-8-6-16(7-9-21)27(35)36/h1-13,15H,14,29H2,(H,31,33)(H,35,36)(H,30,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Agoralaan Abis Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...				J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R
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