Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50309109'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50309109 (CHEMBL589336 | N,N-diethyl-3-(4-methyl-1,4-diazepa...) Show SMILES CCN(CC)c1ncc(nc1N1CCCN(C)CC1)-c1ccncc1 Show InChI InChI=1S/C19H28N6/c1-4-24(5-2)18-19(25-12-6-11-23(3)13-14-25)22-17(15-21-18)16-7-9-20-10-8-16/h7-10,15H,4-6,11-14H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human recombinant ROCK2				Bioorg Med Chem Lett 20: 1137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.012 BindingDB Entry DOI: 10.7270/Q2QR4X7J
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