Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50309116'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50309116 (1-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-y...) Show SMILES C1CCN(C1)c1ncc(nc1N1CCCNCC1)-c1ccncc1 Show InChI InChI=1S/C18H24N6/c1-2-11-23(10-1)17-18(24-12-3-6-19-9-13-24)22-16(14-21-17)15-4-7-20-8-5-15/h4-5,7-8,14,19H,1-3,6,9-13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human recombinant ROCK2				Bioorg Med Chem Lett 20: 1137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.012 BindingDB Entry DOI: 10.7270/Q2QR4X7J
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