Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50309121'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50309121 (CHEMBL602041 | N-methyl-1-(1-(6-(pyridin-4-yl)-3-(...) Show SMILES CNCC1CCN(CC1)c1nc(cnc1N1CCCC1)-c1ccncc1 Show InChI InChI=1S/C20H28N6/c1-21-14-16-6-12-26(13-7-16)20-19(25-10-2-3-11-25)23-15-18(24-20)17-4-8-22-9-5-17/h4-5,8-9,15-16,21H,2-3,6-7,10-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human recombinant ROCK2				Bioorg Med Chem Lett 20: 1137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.012 BindingDB Entry DOI: 10.7270/Q2QR4X7J
					More data for this Ligand-Target Pair