Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50311717'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311717 (2-(chroman-3-yl)-4-fluoro-6-(1H-pyrazol-4-yl)benzo...) Show SMILES Fc1cc(cc2sc(nc12)C1COc2ccccc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C19H14FN3OS/c20-15-6-12(14-8-21-22-9-14)7-17-18(15)23-19(25-17)13-5-11-3-1-2-4-16(11)24-10-13/h1-4,6-9,13H,5,10H2,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311717 (2-(chroman-3-yl)-4-fluoro-6-(1H-pyrazol-4-yl)benzo...) Show SMILES Fc1cc(cc2sc(nc12)C1COc2ccccc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C19H14FN3OS/c20-15-6-12(14-8-21-22-9-14)7-17-18(15)23-19(25-17)13-5-11-3-1-2-4-16(11)24-10-13/h1-4,6-9,13H,5,10H2,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair