Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50311718'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311718 (2-(chroman-3-yl)-4-methoxy-6-(1H-pyrazol-4-yl)benz...) Show SMILES COc1cc(cc2sc(nc12)C1COc2ccccc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C20H17N3O2S/c1-24-17-7-13(15-9-21-22-10-15)8-18-19(17)23-20(26-18)14-6-12-4-2-3-5-16(12)25-11-14/h2-5,7-10,14H,6,11H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311718 (2-(chroman-3-yl)-4-methoxy-6-(1H-pyrazol-4-yl)benz...) Show SMILES COc1cc(cc2sc(nc12)C1COc2ccccc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C20H17N3O2S/c1-24-17-7-13(15-9-21-22-10-15)8-18-19(17)23-20(26-18)14-6-12-4-2-3-5-16(12)25-11-14/h2-5,7-10,14H,6,11H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair