Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50311720'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311720 (CHEMBL1081182 | N1-(2-(chroman-3-yl)-6-(1H-pyrazol...) Show SMILES CN(C)CCN(C)c1cc(cc2sc(nc12)C1COc2ccccc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C24H27N5OS/c1-28(2)8-9-29(3)20-11-17(19-13-25-26-14-19)12-22-23(20)27-24(31-22)18-10-16-6-4-5-7-21(16)30-15-18/h4-7,11-14,18H,8-10,15H2,1-3H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311720 (CHEMBL1081182 | N1-(2-(chroman-3-yl)-6-(1H-pyrazol...) Show SMILES CN(C)CCN(C)c1cc(cc2sc(nc12)C1COc2ccccc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C24H27N5OS/c1-28(2)8-9-29(3)20-11-17(19-13-25-26-14-19)12-22-23(20)27-24(31-22)18-10-16-6-4-5-7-21(16)30-15-18/h4-7,11-14,18H,8-10,15H2,1-3H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	365	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair