Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50311723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311723 (CHEMBL1079919 | methyl 3-(6-(1H-pyrazol-4-yl)benzo...) Show SMILES COC(=O)c1ccc2OCC(Cc2c1)c1nc2ccc(cc2s1)-c1cn[nH]c1 Show InChI InChI=1S/C21H17N3O3S/c1-26-21(25)13-3-5-18-14(6-13)7-15(11-27-18)20-24-17-4-2-12(8-19(17)28-20)16-9-22-23-10-16/h2-6,8-10,15H,7,11H2,1H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311723 (CHEMBL1079919 | methyl 3-(6-(1H-pyrazol-4-yl)benzo...) Show SMILES COC(=O)c1ccc2OCC(Cc2c1)c1nc2ccc(cc2s1)-c1cn[nH]c1 Show InChI InChI=1S/C21H17N3O3S/c1-26-21(25)13-3-5-18-14(6-13)7-15(11-27-18)20-24-17-4-2-12(8-19(17)28-20)16-9-22-23-10-16/h2-6,8-10,15H,7,11H2,1H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair