Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50324579'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50324579 ((R)-N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4...) Show SMILES CCN1Cc2ccc(OC)cc2C[C@@H]1C(=O)Nc1cc(F)c(cc1OCCN(C)C)-c1cn[nH]c1 |r| Show InChI InChI=1S/C26H32FN5O3/c1-5-32-16-17-6-7-20(34-4)10-18(17)11-24(32)26(33)30-23-13-22(27)21(19-14-28-29-15-19)12-25(23)35-9-8-31(2)3/h6-7,10,12-15,24H,5,8-9,11,16H2,1-4H3,(H,28,29)(H,30,33)/t24-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2				J Med Chem 53: 5727-37 (2010) Article DOI: 10.1021/jm100579r BindingDB Entry DOI: 10.7270/Q2833S8C
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50324579 ((R)-N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4...) Show SMILES CCN1Cc2ccc(OC)cc2C[C@@H]1C(=O)Nc1cc(F)c(cc1OCCN(C)C)-c1cn[nH]c1 |r| Show InChI InChI=1S/C26H32FN5O3/c1-5-32-16-17-6-7-20(34-4)10-18(17)11-24(32)26(33)30-23-13-22(27)21(19-14-28-29-15-19)12-25(23)35-9-8-31(2)3/h6-7,10,12-15,24H,5,8-9,11,16H2,1-4H3,(H,28,29)(H,30,33)/t24-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				J Med Chem 53: 5727-37 (2010) Article DOI: 10.1021/jm100579r BindingDB Entry DOI: 10.7270/Q2833S8C
					More data for this Ligand-Target Pair