Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50324581'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50324581 ((R)-N-(2-(2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4...) Show SMILES CN(C)CCOc1cc(ccc1NC(=O)[C@H]1Cc2ccccc2CN1)-c1cn[nH]c1 |r| Show InChI InChI=1S/C23H27N5O2/c1-28(2)9-10-30-22-12-17(19-14-25-26-15-19)7-8-20(22)27-23(29)21-11-16-5-3-4-6-18(16)13-24-21/h3-8,12,14-15,21,24H,9-11,13H2,1-2H3,(H,25,26)(H,27,29)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2				J Med Chem 53: 5727-37 (2010) Article DOI: 10.1021/jm100579r BindingDB Entry DOI: 10.7270/Q2833S8C
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50324581 ((R)-N-(2-(2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4...) Show SMILES CN(C)CCOc1cc(ccc1NC(=O)[C@H]1Cc2ccccc2CN1)-c1cn[nH]c1 |r| Show InChI InChI=1S/C23H27N5O2/c1-28(2)9-10-30-22-12-17(19-14-25-26-15-19)7-8-20(22)27-23(29)21-11-16-5-3-4-6-18(16)13-24-21/h3-8,12,14-15,21,24H,9-11,13H2,1-2H3,(H,25,26)(H,27,29)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				J Med Chem 53: 5727-37 (2010) Article DOI: 10.1021/jm100579r BindingDB Entry DOI: 10.7270/Q2833S8C
					More data for this Ligand-Target Pair