Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50338698'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50338698 (2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)quina...) Show SMILES COc1ccc2OCC(Cc2c1)c1nc2ccc(cc2c(=O)[nH]1)-c1cn[nH]c1 Show InChI InChI=1S/C21H18N4O3/c1-27-16-3-5-19-13(7-16)6-14(11-28-19)20-24-18-4-2-12(15-9-22-23-10-15)8-17(18)21(26)25-20/h2-5,7-10,14H,6,11H2,1H3,(H,22,23)(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 by HTRF assay				Bioorg Med Chem Lett 21: 1844-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.039 BindingDB Entry DOI: 10.7270/Q20G3KFF
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