Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50358697'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50358697 (CHEMBL1922028) Show SMILES COc1cccc(CNC(=O)c2cc3ccc(cc3n2CCN(C)C)-c2cn[nH]c2)c1 Show InChI InChI=1S/C24H27N5O2/c1-28(2)9-10-29-22-12-18(20-15-26-27-16-20)7-8-19(22)13-23(29)24(30)25-14-17-5-4-6-21(11-17)31-3/h4-8,11-13,15-16H,9-10,14H2,1-3H3,(H,25,30)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 21: 7113-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.084 BindingDB Entry DOI: 10.7270/Q2F1905N
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