Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50430338'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50430338 (CHEMBL2333880) Show SMILES Fc1ccc(cc1)[C@@H]1CNC[C@H]1c1nc(N2CCC2)c2cc(ccc2n1)-c1cn[nH]c1 |r| Show InChI InChI=1S/C24H23FN6/c25-18-5-2-15(3-6-18)20-13-26-14-21(20)23-29-22-7-4-16(17-11-27-28-12-17)10-19(22)24(30-23)31-8-1-9-31/h2-7,10-12,20-21,26H,1,8-9,13-14H2,(H,27,28)/t20-,21+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant 6-His-tagged ROCK2 expressed in baculovirus-infected Sf9 cells using LCB-AKRRRLSSLRA-NH2 as substrate after 25 mins b...				Bioorg Med Chem Lett 23: 1592-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.109 BindingDB Entry DOI: 10.7270/Q2TD9ZQM
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