Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50430351'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50430351 (CHEMBL2333903) Show SMILES Clc1ccc(C[C@@H](NC(=O)Cc2cccnc2)c2nc3ccc(cc3c(=O)[nH]2)-c2cn[nH]c2)cc1 |r| Show InChI InChI=1S/C26H21ClN6O2/c27-20-6-3-16(4-7-20)10-23(31-24(34)11-17-2-1-9-28-13-17)25-32-22-8-5-18(19-14-29-30-15-19)12-21(22)26(35)33-25/h1-9,12-15,23H,10-11H2,(H,29,30)(H,31,34)(H,32,33,35)/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant 6-His-tagged ROCK2 expressed in baculovirus-infected Sf9 cells using LCB-AKRRRLSSLRA-NH2 as substrate after 25 mins b...				Bioorg Med Chem Lett 23: 1592-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.109 BindingDB Entry DOI: 10.7270/Q2TD9ZQM
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