Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50431125'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50431125 (CHEMBL2332075) Show SMILES OCCN(Cc1ccccc1)C(=O)Nc1ccc(cc1F)-c1cn[nH]c1 Show InChI InChI=1S/C19H19FN4O2/c20-17-10-15(16-11-21-22-12-16)6-7-18(17)23-19(26)24(8-9-25)13-14-4-2-1-3-5-14/h1-7,10-12,25H,8-9,13H2,(H,21,22)(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF mode				Bioorg Med Chem 23: 2505-17 (2015) Article DOI: 10.1016/j.bmc.2015.03.047 BindingDB Entry DOI: 10.7270/Q2ZP47SX
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50431125 (CHEMBL2332075) Show SMILES OCCN(Cc1ccccc1)C(=O)Nc1ccc(cc1F)-c1cn[nH]c1 Show InChI InChI=1S/C19H19FN4O2/c20-17-10-15(16-11-21-22-12-16)6-7-18(17)23-19(26)24(8-9-25)13-14-4-2-1-3-5-14/h1-7,10-12,25H,8-9,13H2,(H,21,22)(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) after 4 hrs by HTRF assay				J Med Chem 56: 3568-81 (2013) Article DOI: 10.1021/jm400062r BindingDB Entry DOI: 10.7270/Q28C9XMJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50431125 (CHEMBL2332075) Show SMILES OCCN(Cc1ccccc1)C(=O)Nc1ccc(cc1F)-c1cn[nH]c1 Show InChI InChI=1S/C19H19FN4O2/c20-17-10-15(16-11-21-22-12-16)6-7-18(17)23-19(26)24(8-9-25)13-14-4-2-1-3-5-14/h1-7,10-12,25H,8-9,13H2,(H,21,22)(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Technology Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) using STK2 substrate after 4 hrs by HTRF mode				Bioorg Med Chem 23: 2505-17 (2015) Article DOI: 10.1016/j.bmc.2015.03.047 BindingDB Entry DOI: 10.7270/Q2ZP47SX
					More data for this Ligand-Target Pair