Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50442823'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50442823 (CHEMBL2440748) Show SMILES CCCCCCOC(=O)c1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1 Show InChI InChI=1S/C26H29N3O3/c1-2-3-4-5-15-32-26(31)21-8-6-7-19(16-21)24-17-20(9-10-22(24)18-27)25(30)29-23-11-13-28-14-12-23/h6-14,16-17H,2-5,15,18,27H2,1H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Amakem N.V. Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay				Bioorg Med Chem Lett 23: 6442-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.040 BindingDB Entry DOI: 10.7270/Q2BC411W
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