BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribonucleoside-diphosphate reductase large subunit' and Ligand = 'BDBM50000162'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribonucleoside-diphosphate reductase large subunit


(Homo sapiens (Human))		BDBM50000162
PNG
(CHEMBL263439 | Ribonucleotide reductase inhibiting...)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](Cc1cn(C=O)c2ccccc12)NC(C)=O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C48H71N11O16/c1-10-24(6)39(46(72)54-31(17-35(49)63)43(69)53-32(18-37(65)66)44(70)55-33(48(74)75)15-22(2)3)58-45(71)38(23(4)5)57-47(73)40(26(8)61)56-36(64)19-50-41(67)25(7)51-42(68)30(52-27(9)62)16-28-20-59(21-60)34-14-12-11-13-29(28)34/h11-14,20-26,30-33,38-40,61H,10,15-19H2,1-9H3,(H2,49,63)(H,50,67)(H,51,68)(H,52,62)(H,53,69)(H,54,72)(H,55,70)(H,56,64)(H,57,73)(H,58,71)(H,65,66)(H,74,75)/t24-,25+,26-,30+,31+,32+,33+,38+,39+,40+/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.38E+4n/an/an/an/an/an/a



Notre-Dame Hospital Research

Curated by ChEMBL


Assay Description
Inhibitory concentration against HSV-1 ribonucleotide reductase R1 protein binding

J Med Chem 35: 346-50 (1992)


BindingDB Entry DOI: 10.7270/Q2348JB2
More data for this
Ligand-Target Pair