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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase (P70S6K)' and Ligand = 'BDBM50333483'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase (P70S6K)


(Homo sapiens (Human))
BDBM50333483
PNG
(1-[5-tert-Butyl-3-(1,1-dioxo-1lambda*6*-thiomorpho...)
Show SMILES CC(C)(C)c1cc(C(=O)N2CCS(=O)(=O)CC2)c(NC(=O)Nc2ccc3[nH]ncc3c2)s1
Show InChI InChI=1S/C21H25N5O4S2/c1-21(2,3)17-11-15(19(27)26-6-8-32(29,30)9-7-26)18(31-17)24-20(28)23-14-4-5-16-13(10-14)12-22-25-16/h4-5,10-12H,6-9H2,1-3H3,(H,22,25)(H2,23,24,28)
PDB
MMDB

NCI pathway
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UniProtKB/SwissProt

B.MOAD
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of S6K1


Bioorg Med Chem Lett 21: 849-52 (2011)


Article DOI: 10.1016/j.bmcl.2010.11.069
BindingDB Entry DOI: 10.7270/Q289163D
More data for this
Ligand-Target Pair