Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha-3' and Ligand = 'BDBM241959'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM241959 (5-(2-(4-Morpholinophenyl)hydrazono-dihydro-2-thiox...) Show SMILES O=[#6]1-[#7]-[#6](=S)-[#7]-[#6](=O)\[#6]-1=[#7]/[#7]-c1ccc(cc1)-[#7]-1-[#6]-[#6]-[#8]-[#6]-[#6]-1 Show InChI InChI=1S/C14H15N5O3S/c20-12-11(13(21)16-14(23)15-12)18-17-9-1-3-10(4-2-9)19-5-7-22-8-6-19/h1-4,17H,5-8H2,(H2,15,16,20,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.23E+3	n/a	n/a	n/a	n/a	7.4	25
East China University of Science and Technology					Assay Description The inhibition assays against RSK2 in vitro were determined by ADP Quest® (DiscoveRx) in 96-well flat-bottom plates according to the manufacturer...				J Enzyme Inhib Med Chem 28: 747-52 (2013) Article DOI: 10.3109/14756366.2012.681651 BindingDB Entry DOI: 10.7270/Q2DV1HT9
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