Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha-3' and Ligand = 'BDBM50355590'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50355590 (CHEMBL1910599) Show SMILES NC(=N)N\N=C/c1c(nc2sccn12)-c1c(F)cccc1F |(-8.3,-22.83,;-6.76,-22.81,;-6,-21.47,;-5.97,-24.14,;-4.43,-24.12,;-3.65,-25.45,;-4.15,-26.91,;-3.26,-28.17,;-4.19,-29.4,;-5.64,-28.9,;-7.11,-29.36,;-8,-28.1,;-7.08,-26.86,;-5.62,-27.36,;-1.72,-28.18,;-.97,-29.52,;-1.75,-30.85,;.57,-29.54,;1.36,-28.21,;.59,-26.87,;-.94,-26.86,;-1.71,-25.52,)| Show InChI InChI=1S/C13H10F2N6S/c14-7-2-1-3-8(15)10(7)11-9(6-18-20-12(16)17)21-4-5-22-13(21)19-11/h1-6H,(H4,16,17,20)/b18-6-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
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