Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha-3' and Ligand = 'BDBM50360295'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50360295 (CHEMBL1933282 | US9150577, 76) Show SMILES O=C(Nc1nc2ccccc2n1-c1ccccc1)c1ccc2cc3C(=O)NCCCn3c2c1 Show InChI InChI=1S/C26H21N5O2/c32-24(18-12-11-17-15-23-25(33)27-13-6-14-30(23)22(17)16-18)29-26-28-20-9-4-5-10-21(20)31(26)19-7-2-1-3-8-19/h1-5,7-12,15-16H,6,13-14H2,(H,27,33)(H,28,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer-Ingelheim Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of human RSK2				Bioorg Med Chem Lett 22: 738-42 (2011) Article DOI: 10.1016/j.bmcl.2011.10.029 BindingDB Entry DOI: 10.7270/Q2348KTR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50360295 (CHEMBL1933282 | US9150577, 76) Show SMILES O=C(Nc1nc2ccccc2n1-c1ccccc1)c1ccc2cc3C(=O)NCCCn3c2c1 Show InChI InChI=1S/C26H21N5O2/c32-24(18-12-11-17-15-23-25(33)27-13-6-14-30(23)22(17)16-18)29-26-28-20-9-4-5-10-21(20)31(26)19-7-2-1-3-8-19/h1-5,7-12,15-16H,6,13-14H2,(H,27,33)(H,28,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer-Ingelheim Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assay				Bioorg Med Chem Lett 22: 738-42 (2011) Article DOI: 10.1016/j.bmcl.2011.10.029 BindingDB Entry DOI: 10.7270/Q2348KTR
					More data for this Ligand-Target Pair