Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ribosyldihydronicotinamide dehydrogenase [quinone] (Homo sapiens (Human)) | BDBM11323 (4,5,6,7-tetrabromo-1H-1,2,3-benzotriazole | 4,5,6,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Western Ontario | Assay Description To determine the IC50 value of each inhibitor, reactions were initiated by addition of 154 pM NQO2 to a reaction buffer containing 150 μM SCDP a... | Biochemistry 54: 47-59 (2015) Article DOI: 10.1021/bi500959t BindingDB Entry DOI: 10.7270/Q2BV7FC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosyldihydronicotinamide dehydrogenase [quinone] (Homo sapiens (Human)) | BDBM11323 (4,5,6,7-tetrabromo-1H-1,2,3-benzotriazole | 4,5,6,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | 7.11E+3 | n/a | n/a | n/a | n/a | n/a |
University of Western Ontario | Assay Description To assess direct binding of inhibitors to oxidized NQO2 (NQO2ox), fluorescence quenching of FAD was monitored with an excitation wavelength of 350 nm... | Biochemistry 54: 47-59 (2015) Article DOI: 10.1021/bi500959t BindingDB Entry DOI: 10.7270/Q2BV7FC9 | |||||||||||
More data for this Ligand-Target Pair |