Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ryanodine receptor 1' and Ligand = 'BDBM50016405'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ryanodine receptor 1 (Oryctolagus cuniculus)	BDBM50016405 (2,6,9,11,13,14-hexahydroxy-11-isopropyl-3,7,10-tri...) Show SMILES CCCCn1cccc1C(=O)O[C@@H]1[C@](O)(C(C)C)[C@]2(C)[C@]3(O)C[C@@]4(C)[C@@]5(O)CC[C@H](C)[C@@H](O)[C@]5(O3)[C@]2(O)[C@@]14O |r,THB:18:20:25:35.37,21:20:25:35.37| Show InChI InChI=1S/C29H43NO9/c1-7-8-13-30-14-9-10-18(30)20(32)38-21-26(35,16(2)3)23(6)25(34)15-22(5)24(33)12-11-17(4)19(31)28(24,39-25)29(23,37)27(21,22)36/h9-10,14,16-17,19,21,31,33-37H,7-8,11-13,15H2,1-6H3/t17-,19+,21+,22-,23+,24-,25-,26+,27+,28+,29+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...				J Med Chem 30: 710-6 (1987) BindingDB Entry DOI: 10.7270/Q26M37D3
					More data for this Ligand-Target Pair