Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ryanodine receptor 1' and Ligand = 'BDBM50016409'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ryanodine receptor 1 (Oryctolagus cuniculus)	BDBM50016409 (2,6,11,14-tetrahydroxy-11-isopropyl-9,13-dimethoxy...) Show SMILES CO[C@@]12C[C@@]3(C)[C@@]4(O)CC[C@H](C)[C@@H](O)[C@]4(O1)[C@@]1(O)[C@]2(C)[C@@](O)(C(C)C)[C@@H](OC(=O)c2cccn2C)[C@@]31OC |r,THB:18:2:6:16.35,1:2:6:16.35| Show InChI InChI=1S/C28H41NO9/c1-15(2)25(33)20(37-19(31)17-10-9-13-29(17)6)27(36-8)21(4)14-24(35-7)22(25,5)28(27,34)26(38-24)18(30)16(3)11-12-23(21,26)32/h9-10,13,15-16,18,20,30,32-34H,11-12,14H2,1-8H3/t16-,18+,20+,21-,22+,23-,24-,25+,26+,27+,28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...				J Med Chem 30: 710-6 (1987) BindingDB Entry DOI: 10.7270/Q26M37D3
					More data for this Ligand-Target Pair